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Although a small number of functional assessment scales have been developed and validated for use in other LMICs (see Table 1), of these, only a proportion addressed face validity issues by involving the local population in development (31, 32).
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Direct tracking of class II MHC-restricted epitope-specific CD4 T cells will help to elucidate evolution or differentiation of Th1, Th2, Th17 and Treg cell populations in development of balanced anti-microbial immunity against viral or bacterial infections.
Stem cells can also provide intermediate populations in development whereas mature cells isolated from adult tissue cannot.
Embryonic stem cells (ESCs) can be used as an experimental system to probe the mechanisms that mediate the specification and differentiation of cell populations in development.
Nanog is crucial in driving establishment of pluripotency during specification of the pre-implantation epiblast and for maintenance of the specified PGC population later in development.
The remainder generally specified the target population, had clear aims and concepts but either did not involve the target population in the development nor undertook pilot work.
To address and overcome potential barriers and cultural misunderstandings, it is crucial to involve the target population in the development of study design and recruitment.
Malfunction of the cardiac NC affects the caudal cardio craniofacial field whereas the involvement of cranial NC population in cardiac development is far less studied.
The other significant meta-regression finding indicated that studies that engaged their target population in the development, implementation, and/or evaluation of the intervention were more likely to report a beneficial intervention effect for dichotomous behaviour outcomes.
Second, we screened for evidence of a genetic differentiation between populations in juvenile development time by comparing cumulative distributions of development times from egg to pupal stage, given that individuals pupated.
Civil Society Organisations should be in the vanguard, positioning reproductive health as a central issue in population and development in Nigeria.
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