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Population imaging focusses on finding imaging biomarkers that allow early diagnosis of preclinical disease and prediction of clinical disease.
Population imaging endeavors to find imaging biomarkers that can predict later development of disease, either on their own or by supplementing established risk factors.
We then tested the hypothesis that nAChRs activate the PFC in a layer-specific manner using 2-photon population imaging.
The reported incidence of CIN varies among studies, due to differences in definition, type and dose of contrast medium, study population, imaging procedure and the frequency of other potential causes of AKI [ 1].
Since flow cytometry only gives data regarding total shifts in fluorescence of a population, imaging flow cytometry and live imaging microscopy studies were performed to determine if the NLS augmented nuclear accumulation of the peptides.
While new 2D scan techniques for in vivo population imaging achieve sampling rates from ten up to several hundred Hertz [ 5], typical maximum 3D scanning rates are lower, mostly due to the limit set by the inertia of the moving objective.
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Screening a clinically healthy population with imaging to detect and characterise these subclinical abnormalities and to treat the individuals at risk might be an optimal strategy in preventive medicine.
Nonetheless, we do believe that our study sample is comparable to the target population of imaging practitioners, particularly since the characteristics represented in our study sample are consistent with those of the relatively young workforce of radiology practitioners and radiographers at the hospital studied.
Using population calcium imaging and targeted patch recordings in thalamocortical slices, we demonstrate that the stereotyped patterns of multineuronal activations present during both spontaneous and thalamically triggered UP states are essentially unaffected by thalamic inputs.
Using in vivo two-photon population Ca2+ imaging in awake mice, this study investigated how neural representation of visual input to PFC neurons is regulated by dopamine.
Although the mechanism of this labeling specificity is unknown, this property might also contribute to better SNRs in population calcium imaging in vivo.
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