Previous work on this population has focussed on marker-based estimators as a proxy for inbreeding because sample sizes for pedigree based measures were previously too small [ 47].
Furthermore, few gene studies performed on the Chinese population have focused on COPD.
Few gene studies of the Chinese population have focused on COPD.
For example, the only reported HIV studies in the Guyanese population have focused on HIV prevalence in commercial sex workers in the capital city of Georgetown (2 ).
To date, studies comparing the relative risk of VFs among AS patients and the general population have focused on clinical VFs [ 6, 10].
population have focused primarily on mitochondrial genes encoding subunits I or II of cytochrome oxidase (CO I or CO II) [ 14, 15, 31- 33].
Previous efforts to assess whole grain consumption in the French population have focused only on the number of servings of whole grain foods, without specifically quantifying absolute whole grain intake or differentiating whole grain sources.
Most early studies on self-assessed health among the diabetic population have focused on diabetes-specific attributes, such as the duration of diabetes [ 9], diabetes complications [ 10], and the use of insulin [ 11].
Most studies of sARF in the critically ill population have focused on mortality and renal recovery at ICU and hospital discharge, therefore viewing sARF as an acute and short-term illness [ 3- 5, 8, 9, 11, 18, 21, 36].
Studies of healthy individuals, including the Chinese population, have focused on particular body habitats, such as the gastrointestinal tract, nasopharynx, skin, and oral cavity, using high-throughput sequencing techniques [ 16, 20- 28], and have revealed microbial communities with significant intra- and inter-individual variations [ 27, 29].
