"Have you read Aldous Huxley's Brave New World with its population graded from the top, Alpha, down to Epsilon?" she asks, begging the question of how closely she read it herself.
This prevalence of VFs in our population (grade 2/3) is similar to figures reported in western Caucasian population [ 15].
In our study population, grade 4 toxicities were rare (<1%); nonetheless, grade 3 neutropenia was present in nearly one third (30.3%) of patients.
After radiotherapy, there were occurrences 32 (20.0%) of grade ≥2 radiation pneumonitis (RP) in our population (grade 2, grade 3, and grade 4 were observed in 4, 24, and 4, resp).
In this population, grade 3 or 4 cardiotoxicity was associated with low BMI (mean 23.9 kg m−2 vs 27.1 kg m−2; P=0.03).
For the overall study population, grade 3 4 nausea, vomiting, ileus, and fatigue toxicity occurred significantly more frequently in the nonresection compared to the resection group, 9% vs. 3% for nausea (P = 0.004), 9% vs. 4% for vomiting (P = 0.043), 8% vs. 3% for ileus (P = 0.019), and 23% vs. 13% for fatigue (P = 0.004), respectively.
Safety results across the patient subgroups for trial CA012 were similar to the ITT population: grade 3/4 neutropenia was more frequent for paclitaxel in the poor prognostic factor subgroups, whereas sensory neuropathy and fatigue were both more frequent for nab-paclitaxel (Table 5).
21 education systems around the globe participated in ICILS 2013, whose research design defined two target populations: Grade 8 students and teachers teaching in Grade 8 (Jung and Carstens 2015).
As detected by confocal imaging of Rhod-2 AM and MitoFluor Green dyes within live populations, grade 3 tumor cells displayed significantly reduced [Ca2+]m in comparison with grade 1 cells.
