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For each generation, we prepared a mutant library from the parental population enriched at the previous generation and continued the iterative enrichment process until the increase in infectivity seemed to cease.
Rosca, A. M. & Burlacu, A. Isolation of a mouse bone marrow population enriched in stem and progenitor cells by centrifugation on a Percoll gradient.
The population enriched in less circular flocs (i.e. 20% flocs with circularities >0.5) had a lower tailing level (at least by 1-log) compared to the other population.
We investigated the stem cell characteristics and differentiation potential of a chorionic derived population enriched in c-Kit+ cells and compared this to the unenriched population.
In the phase II study, the combination of tivantinib plus erlotinib significantly improved progression-free survival (PFS) and overall survival (OS) compared with placebo plus erlotinib in the subset of patients with nonsquamous histology, a population enriched for MET overexpression.
Using in vitro functional assays, we found that this antibody can be used to sort a CD34+CD38−CD110+ population enriched in hematopoietic progenitor stem cells, both in CB and in adult BM.
Pax7 was highly expressed in the CD11b-/Ly-6G population, suggesting that this population enriched the satellite cells.
A significant difference between native and C1213L neurofascin is that these proteins were localized in distinct fractions within a low-density membrane population enriched in signaling molecules.
We surveyed 207 single-nucleotide polymorphisms in 110 candidate genes among coronary artery disease patients, a population enriched for metabolic abnormalities.
We have used this technique of hybridization subtraction chromatography to select a mRNA population enriched for the mRNAs inducible by ecdysterone in Schneider's Line 2 Drosophila cells.
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We now show that a sub-population enriched in tumor-initiating cells upregulates both EP4 and COX-2.
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