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The following data were extracted in a standardized manner from eligible studies: first author, publication year, country, study design, characteristics of the study population, duration of follow-up, PC incidence/PC mortality according to serum vitamin D status and the respective risk ratios, and covariates adjusted for in the analysis.
The following data were extracted in a standardised manner from eligible studies: first author, publication year, country, study design, characteristics of the study population, duration of follow-up, BC incidence/BC mortality according to serum 25-hydroxyvitamin D (25(OH D) and the respective ratios, and covariates adjusted for in the analysis.
There was very little variation in the subgroups as regards population, duration of the intervention and recruitment method.
The originality of this project is based on three criteria: the choice of the study population, duration of follow-up and inclusion of patients from different CBUs.
We specifically abstracted information on the following: population; duration of time outside of Tibet; number of children, clergy, elderly, and women; access to mental health services; and mental health outcomes (PTSD, anxiety and depression) identified using standardized measurement tools.
Marketing authorization holders run randomised controlled trials for regulatory purposes, whose design deviates from real life settings due to comparator choice, exclusion and inclusion criteria, patient population, duration of the trials, setting, outcome measures and duration.
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The populations, duration of dosing and days of sampling for all trials are shown in Table 1.
The eligible trials of treatment duration in pyelonephritis involved diverse patient populations, durations of treatment, and outcome measures, and this explains the heterogeneity of outcomes with shorter durations of therapy.
Heterogeneity of results is not evidence against a causal effect but is an interesting finding that should be interpreted in consideration of the impact of both non-causal as well as causal explanations; the latter include differences in populations, durations of follow-up and doses.
Clustering does not prove that transmission occurred, and its demonstration depends on adequate sampling of the population, incidence of TB, and characteristics of the study population (e.g., age structure, population mobility, duration of residence, and immune status) (1, 13).
Further stratified analyses on the whole study population comparing AHT users and the general population for duration of follow-up (1, 1 4 and 5 or more years) and number of prescriptions (2 4, 5 9, 10+ prescriptions) were also performed.
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