Sentence examples for population difficult from inspiring English sources

Study limitations (eg, trial design, analytic methodology, patient selection criteria, and lack of specificity of therapeutic intervention), however, have made the applicability of findings to a general AF patient population difficult.

However, in a relatively stable environment such as along the Fall River, muskat burrows and houses tend to be long-lasting structures, making acute changes in population difficult to detect by these methods.

Fluctuating breeding populations and high mobility of colonies make estimating the population difficult.

This makes generalization to the entire Indian population difficult.

Homosexual activities face strong negative social pressure in China, which has made the MSM population difficult to reach [ 17].

We acknowledge that some limitations of our study make the extrapolation of our results to the general population difficult.

The infrequency of these fractures has made the study of large patient populations difficult; multiple small studies constitute the majority of the available literature on this topic.

Low pH, abundance of mineral particles, presence of microorganisms in biofilms and the species diversity of microorganisms inhabiting the biomining environment has made studying these populations difficult.

The spontaneous transition of Epstein-Barr virus (EBV) from latency to productive infection is infrequent, making its analysis in the resulting mixed cell populations difficult.

The wide range of methodological approaches for the quantification of co-activation index (CI) makes comparisons across studies and populations difficult.

Complex migration patterns of Coastal Cutthroat Trout resulted in a mixed stock fishery for most of the year and have the potential to make protection of smaller populations difficult in the marine environment.