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The proposed approach is verified and validated by proposing an experimental analysis where it is evaluated a set of construction projects (i.e. digging wells) in a stabilization area and their effectiveness both in terms of direct result (i.e. water availability) as well as of population consensus and disaster relief (i.e. stress mitigation, trustiness respect supporting players).
Positions that varied relative to the genotype 1a or 1b population consensus sequence were identified with Mutation Master [34].
Amino acid positions that varied relative to the genotype 1a population consensus sequence [32] were identified using Mutation Master [61].
The genotype 1b population consensus reference sequence was generated from all 126 full-length ORFs from different patients in the databases in January, 2006.
We first compared the number of variations in the SVR or NR sequences relative to a genotype 1a or 1b population consensus reference sequence.
The second model was estimated from alignments where every sequence represented a population consensus from a patient (between individual, HIV between, HIV-Bm).
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To monitor adaptive substitutions, we introduce a population-consensus genome G that keeps track of all polymorphic loci, that is, of all mutant alleles that are segregating in the population.
The aim is to propose and test on large population a consensus protocol for managing MOH.
Figure 2B reveals the sparsity of the reactivity afforded by some variants, underlining that variant peptides do not elicit the same degree of recognition in the population as consensus peptides.
Folding analyses were also performed for population specific consensus sequences as determined previously [ 33].
These studies suggest that characterizing RNA virus populations as a whole, rather than focusing on dominant viral haplotypes (e.g. sequences shared by a significant amount of members in the population) or consensus sequence is far more informative to study pathogenesis.
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