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The most populated class of domain architectures is represented by the 14 MAPK phosphatases of the DSP family that are associated to a Rhodanese-like domain.
Not surprisingly, Euler assignment using the RCT model from the most populated class gave a reconstruction that had the most structural detail.
One-third of the correct predictions from WoLF PSORT were for cytoplasmic proteins, which was overall, the most populated class for human proteins in LocDB (Supplementary Table S2).
For instance, a subclass with a classification code αβ4.1.1 means that: it belongs to type α β, it is the most populated class αβ4.1 with loops of length 4 ± 1 and it is the most populated subclass αβ4.1.1.
We are well aware that the relatively low density of the Illumina arrays with respect of other methods (CGH arrays, whole re-sequencing) make the detection of short CNVs very hard, while it is very well documented, by deep-sequencing methodologies that in Homo sapiens[ 18, 55] and more recently in Bos taurus the most populated class of CNVs is that of variants shorter than 50 kb [ 39, 40].
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As shown in Fig. 4A, many populated class-average images show well resolved structural features for both 60S subunits, indicating that inter-subunit connection could be rather rigid (Fig. 4A).
It also shows that the prediction errors per class are lowest for the most populated classes.
Table 6 shows the number of days per class and the <δ_pred> adjustment per class, which is better for the most populated classes.
Figure 9 shows the CSDB coverage in various domains, phyla and most populated classes.
The other most populated classes were ubiquitin-related proteins and actors of the photosynthesis.
We focus here on the most populated classes: mitogen-activated protein kinase; circadian clock; calcium oscillations; cell cycle.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com