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Since the pathogenesis of IBS is still poorly understood, the question arises whether the intake of medication can contribute to or trigger onset of symptoms in IBS patients, as these patients often utilize medications that may potentially alter intestinal homeostasis.
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Too poorly understood, the IPCC authors said.
One poorly understood question is the role of BACE1 in the brain, the target organ of BACE1 inhibitors.
In this manuscript, Siebert et al. use the fly larval NMJ system to study the important but poorly understood question of active zone transport.
While in mammals the recruitment of SUV39H and the formation and spreading of heterochromatin at pericentromeres is only poorly understood, this critical question of establishment is better understood in Schizosaccharomyces pombe, and involves the RNA interference (RNAi) machinery (see next).
How cell type identity is maintained at the molecular level is a central but poorly understood question in biology.
The pathogenesis of this disease is still poorly understood, and fundamental questions regarding the precise molecular nature and biological significance of the inflammatory changes remain to be answered [ 1, 2].
How such enzymes are specifically targeted to LDs is a poorly understood, yet fundamental question.
Understanding how novel traits arise from pre-existing variation remains one of the most challenging and poorly understood questions in evolutionary biology.
However, the process of pyritization is still poorly understood and many questions remain unanswered; for instance, if it is a selective process, how do the internal tissues or cell interior become pyritized?
Poorly understood questions, or underutilized rating scale categories can seriously impair the accuracy and reliability of PRO measurements [ 6- 8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com