Taken together, those results indicate the possibility of using cholesterol inhibitors as treatment or chemopreventive agents for PCa metastasis, but novel drugs are then needed as the statins used today primarily concentrate to the liver and poorly reach peripheral organs [17].
Prescription opioid users may be poorly reached by traditional drug treatment services, although treatment admissions in New York State do display a steady increase from this group over the past 15 years.
Acute infections are hardly recognized but, since most HIV infections acquired in advanced ages are sexually transmitted, association with other STI is expected in this subset of patients who are not aware of own their risk, mode of HIV transmission and seem poorly reached by health education programs on safe sexual behaviour.
As children eagerly embrace their freedom, while abiding by rules and expectations, they will sometimes over-reach, choose poorly, make mistakes and need advice.
The relationship starts out poorly but blossoms, reaching across social and racial boundaries.
In Huiskes seminal paper "Failed innovation in total hip replacement: diagnosis and proposals for a cure", finite element modelling was one of the potential cures to avoid poorly performing designs reaching the market place.
As shown in the literature, reaching poorly regulated T2D patients and improving their adherence can be fostered by several factors: a.
Also interestingly, at ZEEP Ers increased to values similar to those observed at a PEEP of 12 cmH2O and the CT images showed an increase in poorly aerated areas (reaching 15% of the region of interest); non-aerated areas remained close to zero.
The Swedish army defended Finland poorly, with that defense reaching its nadir when the strong fortress of Sveaborg near Helsingfors was handed over to the Russians by treason.
If a crisis is poorly managed, society reaches this point sooner rather than later.
