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Aminoglycosides and quinolones are poorly efficacious.
The current treatment for leishmaniasis is complex, expensive, and poorly efficacious.
The current treatment options for nail psoriasis are poorly efficacious, and patients need long-term treatments in order to obtain any clinical benefit.
The treatment options for IBS are limited and for a group of patients (typically those seen in secondary care settings [ 9]) available treatment may be poorly efficacious.
For example, for the large numbers of individuals suffering symptoms of irritable bowel syndrome (IBS) where conventional treatment is often poorly efficacious, the potential for alternative evidence based therapies is considerable.
Additional studies with PPSV23 have shown that this vaccine is often not immunogenic and poorly efficacious in HIV-infected children and adults who have or have not received HAART [ 10– 13].
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Currently, animal models for SUCLA2 deficiency are lacking, the underlying disease mechanisms are poorly understood and no efficacious treatments are available.
This is particularly problematic in the context of poorly resourced healthcare settings where even efficacious interventions fail to translate into improvements in health.
Our findings demonstrate that appropriate use of SMBG in poorly controlled, insulin-naïve type 2 diabetic patients can be efficacious and clinically meaningful.
Among carefully screened patients, bariatric surgery has proven safe and efficacious in the management of clinically severe obesity and poorly controlled type 2 diabetes.
The tirapazamine (TPZ) is efficacious in the treatment of different human cancer cells via inducing DNA damage in poorly oxygenated tumor cells [22].
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