Sentence examples for poorly defined target from inspiring English sources

Possible drawbacks in study design, including lack of standardized case definitions, poorly defined target populations, inappropriate dose selection and measurable outcomes, and brief study durations may have masked true underlying mechanistic effects of previously investigated adjuvant therapies for HAND in specific patient populations.

The authors also theorized that the lower obliteration rate observed with preradiosurgical embolization was attributable to the recanalization of the embolized portion of the nidus as well as the difficulty with radiosurgical planning since embolization may convert a fairly uniform geometric target into a poorly defined target with multiple irregular components.

These additional parameters include a relationship type, a multi flag (for poorly defined targets) a complex flag (for protein complex targets) and a curation level.

Though poorly defined, targeting ATP release mechanisms in leukocytes have great anti-inflammatory potential.

However, pollution also can influence environmental AR, particularly associated with heavy metal, pharmaceutical, and other waste releases, although the relative scale of the "pollution" contribution is poorly defined, which restricts targeted mitigation efforts.

As the initiating events leading to OA are still poorly defined, clinical intervention still targets the reduction of pain and discomfort in afflicted patients.

For B-cell tumors, immunoglobulin idiotypic antigens provide defined targets but are poorly immunogenic.

We chose to target a poorly defined human serine-threonine kinase, Nuclear Dbf-2 Related (NDR).

These poorly defined conditions are nonetheless the target of many investigations seeking to unravel risk factors for their causation or severity.

In hepatocytes, FA are taken up by transporters [ 45], followed by poorly defined trafficking of FA to target organelles such as mitochondria and peroxisomes to undergo oxidation.

When there's no clear understanding of the customer, and when targets are poorly defined, nothing good can happen.