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BDG fared the best in terms of specificity at 38.46 % while CS had the poorest specificity at 15.38 %.
For females, specificity was poorest (specificity = 0.45 to 0.55), however sensitivity was perfect (sensitivity = 1.0) (Table S2 in Additional file 2).
Except for Milwaukee, the 7-day filter tends to have higher sensitivities compared to the other filters, but also tends to have the poorest specificity.
The poorest specificity was obtained when MRI scans were considered positive when only one or more cerebral cortical region showed a high signal; therefore, those patterns were excluded for further analysis.
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D-dimer assays are sensitive but have poor specificity.
A key factor responsible for the poor specificity and poor efficacy of CAR-T against malignant epithelial cells is the lack of specific targetable antigens.
OST predicts osteoporosis with moderate sensitivity and poor specificity in men.
However, numerous studies show that this approach has poor specificity and a high degree of subjectivity.
Current approaches to assess Akt activation rely on intensity-based methods, which are limited by the subjectivity of manual scoring and poor specificity.
Preliminary analysis found that the simple checklist as originally conceived had excellent sensitivity (96%) but poor specificity (10%).
Computerized drug prescribing alerts can improve patient safety, but are often overridden because of poor specificity and alert overload.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com