Exact(4)
In contrast, NFAT5−/− cells failed to induce osmoprotective genes and exhibited poorer viability.
In parallel experiments, we observed that NFAT5−/− T cells exposed to hypertonicity during 24 hours exhibited poorer viability (56%) than wild-type cells (70%) (Fig. 1B), and those surviving displayed cell cycle defects, with cultures having a lower proportion of cells in S, and a greater accumulation in G1 and G2/M (Fig. 1C).
Altogether, these results indicated that hypertonicity triggered a rapid cell cycle arrest in both wild-type and NFAT5−/− T cells, but while the former induced osmoprotective gene products and resumed proliferation with only a moderate viability loss, NFAT5−/− cells had poorer viability, and those surviving exhibited cell cycle defects.
In that study, harvesting of the largest individuals, which is analogous to trawling, led to heritable changes towards smaller fish, slower growth, reduced fecundity, poorer viability of larvae, and diminished yield.
Similar(56)
However, the cells cultured on bare TNAs exhibited a poor viability (48%%).
However, progress in cell therapy is hampered by poor viability of implanted cells and the vulnerability of regenerated tissue to repeated bouts of ischemia.
The traditional clinical methods of bone defect management, such as autografts and allografts of cancellous bone, can be limited by the large size of bone defects, poor viability of host environment and unpredictable graft resorption (Burg et al. 2000).
Embryonic stem cells (ESCs) have been used as an alternative cell source for cardiac repair; however, dissociated ESCs show poor viability in the scaffold and do not form the embryoid body (EB -like structurEB -like
However, the outcomes of existing treatments have not been satisfactory owing to suboptimal localization to implantation site, poor viability, low engraftment efficacy and lack of functional remodeling of the delivered cells.
CDOT and CSP will keep US 160 closed due to poor viability, heavy smoke and the fire's proximity to the highway.
However, those cells had poor viability, showing mainly nuclear integrity.
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