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The relatively poor outcome in adult ALL has been explained by an increased frequency of high-risk molecular subtypes with more aggressive clinical behavior and greater drug resistance, poorer tolerance and compliance with treatment, and less effective treatment regimens compared with childhood ALL [6], [8], [9].
A high incidence of asynchrony is associated with a poorer tolerance of NIV.
There may be poorer tolerance to treatment, and health conditions in older patients.
Patients who failed NIV had lower PEEP levels and poorer tolerance to NIV than patients who succeeded NIV.
Furthermore, their increased frequency of comorbidities and decreased performance status at the time of diagnosis leads to poorer tolerance to therapy compared to younger patients.
Furthermore, the outcomes are less favorable in adults, whose complete recovery rates rarely exceed 40% and who exhibit greater resistance to, and poorer tolerance of, therapeutic agents compared to children [ 2].
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Generic recommendation #7 leads to apply the recommendations for poor tolerance when the treatment is both ineffective and poorly tolerated, because in case of poor tolerance, the patient's adherence to the treatment is often low and therefore the efficacy of the treatment cannot be rigorously evaluated.
"There's been quite a poor tolerance for them and quite a poor attitude towards them," she says.
But these strategies may not work — hyperacusis sufferers may be furthering their poor tolerance to relatively soft sounds.
I learned that I have a very poor tolerance for pain, and I had time to consider every fantasy of my youth in which I resisted some torturer for a cause of right.
Failure and/or poor tolerance of abortive drugs 5.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com