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Patients who met criteria also demonstrated poorer role functioning, less vitality, and more depressive symptomatology (P ≤ 0.05).
Women with complications or systemic therapy had poorer role, emotional, cognitive and social functioning than their counterparts without these factors.
Patients meeting criteria reported higher levels of fatigue severity, frequency, pervasiveness, and interference with quality of life and poorer role functioning, less vitality and more depressive symptoms.
They suggest that the difference between the study results is because of disruption to women's lives from delivery of continuation therapy that was reflected in poorer role functioning, financial worries, attitudes to disease to treatment, hormonal symptoms and rash.
Adding modifiable factors, poorer role (P<0.001) and social functioning (P=0.003), fatigue (P=0.001), dyspnoea (P=0.001), anorexia (P<0.001), depression (P<0.001) and worse perceived consequences (P=0.013) improved the model fit considerably (R=0.574).
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