We anticipate that this insight will allow studies using OBOC libraries to proceed more efficiently by eliminating unproductive postscreening resynthesis and analysis of what eventually prove to be poor quality compounds.
The provision of poor-quality care has often been attributed to inadequate knowledge and skills compounded by broader system failures and low staff numbers.
I sold poor-quality double glazing.
Dump poor-quality pieces, too.
72, 86, 87 To combat the entry of both counterfeit and substandard artemisinin compounds, both national and international regulatory authorities need to strengthen drug quality monitoring to deter the introduction and circulation of poor-quality antimalarials.
Its economy and speed of production have inevitably led to its use on buildings of poor quality – frequently compounded by substandard design and inadequate maintenance.
Caustic washing is used to remove corrosive and pungent sulphur compounds from poor quality crude oil so that it can be blended into petrol and diesel.
Yet the poor quality of new jobs is compounding the problem of the working poor, says Kaori Katada, a sociologist at Hosei University in Tokyo.
When the severity of environment is compounded with poor quality concrete and/or defective design and construction practices, the process of deterioration becomes interactive, cumulative and very rapid, and a cancerous growth that cannot be easily stopped.
This problem is compounded by poor qualities of data collection and management systems, particularly in low-income settings, which make it difficult to capture actual rates of attendance and enrolment.
A meta-analysis of RCTs, all of which have a similar defined outcome, can be useful if the original studies are underpowered, but meta-analysis of poor quality data will not improve them and may simply compound the uncertainty.
