Sentence examples for poor transcript from inspiring English sources

The decreased expression of the CD3ζ chain in SLE T cells has been attributed to defects at multiple levels, including defective gene transcription [ 16], aberrant mRNA splicing [ 17], poor transcript stability of alternative splice variants [ 18], and increased protein degradation by caspase-mediated [ 19], ubiquitin-proteasome-mediated and lysosomal-mediated mechanisms [ 20].

Consequently, using just 1-kbp genomic regions as done previously [14], likely predict poor transcript models with high frequency.

Consequently, our measurements of nucleotide-level changes were not dependent on the quality of the transcriptome, except that some regions of the gene may be missing due to poor transcript coverage.

For a more refined control of novel isoforms, or for organisms with poor transcript annotations, users are suggested to perform novel transcript assembly using tools like Cufflinks [22] and then load the resulting gene and transcript annotations (GTF) into PrimerSeq.

Whether low maternal transcript levels are the result of a lack or sub-optimal polyadenylation during Atlantic halibut oocyte maturation, leading to poor transcript translation and/or degradation in low quality early embryos, requires further investigation.

The presence of non-orthologous genes in other species should be considered as a central resource to derive important information for the definition of gene models and structures, in particular for the newly assembled genomes, where the lack of a complete set of genes and poor transcript sequences information may restrict the commonly applied annotation procedures.

Clay et al. [ 14] looked at CpG islands upstream of GC-rich and GC-poor transcripts and found little correlation.

Overall, this study suggests that the short syncytial cycles in early Drosophila embryogenesis favor transcripts with a simple gene-architecture consisting of short, intron-poor transcripts (Fig. 2).

The conserved trend toward short, intron-poor transcripts among the first zygotically expressed genes extends to the mouse [ 44], even though the first cell cycles are longer than in fly, frog, or zebrafish embryos.

To examine a possible interrelation with the target prediction preference for long and GC-rich sequences, the 1,000 longest and GC-richest, as well as the 1,000 shortest and GC-poorest transcripts, were tested.

To examine a possible interrelation between the annotated biological function and the preference of target predictions for long and GC-rich sequences, the 1,000 longest and GC-richest, as well as the 1,000 shortest and GC-poorest transcripts were tested for over-represented and under-represented terms with the same significance cutoff.