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"Countries with a large gap between rich and poor often have large subpopulations of extremely poor individuals.
In stage II-III colorectal cancer, BRAF mutation was confirmed a marker of poor survival only in subpopulations involving microsatellite stable and left-sided tumors, with higher effects than in the whole population.
The difference between English- and Spanish-language Hispanics with regard to environmental concern persisted among relatively poor and more affluent subpopulations, among more and less educated, and among residents of New Jersey's larger cities and other environments.
For both provinces, the level of insurance premiums excluded a subpopulation of poor people from health coverage [ 4].
A 'proliferation signature' has been shown to identify particular patient groups who have an extremely poor outcome in a subpopulation of breast cancer patients [ 17].
The analysis of approved subpopulations showed poorer complete reporting of results items, particularly in non-AMNOG documents (non-AMNOG versus AMNOG: 11% v 71% for overall results items and 5% v 70% for patient relevant outcomes).
Of particular significance, we identified a patient subpopulation with poor survival using member genes in disrupted pathways, implying the potential of these disrupted pathways to serve as a guide to therapy in a subgroup of patients.
This further confirms that the observed tumourigenicity is a characteristic of ALDH− cells, and not a result of poor separation of the two subpopulations.
The algorithms published by Jang, Longworth and McKenzie map relatively well in the subpopulation with very poor health (observed EQ-5D less than 0.5) with a deviation from observed mean of 0.09, 0.17 and 0.13 respectively.
This could cause some population health metrics to decrease because these subpopulations are generally in poorer health.
Second, TYRP1 mRNA expression was significantly higher (P<0.001, Mann Whitney test) in the subpopulation of patients with poor prognosis (group 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com