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However, the poor solubility and bioavailability limit its application.
The poor solubility and bioavailability of many drugs causes constraints.
A class IV drug, roxithromycin (ROX), has poor solubility.
Plausible reasons for the poor solubility are cross-linking reactions, inherently poor solubility of the zinc complexes, and complexation with ZnO produced as a byproduct (discussed later).
This poor solubility of β-CD did not allow the direct dissolution for electrospinning.
We considered the reason for the poor solubility of the products obtained from other TSHs.
However, its clinical application is limited by poor solubility, low stability, and high toxicity.
Most anticancer drugs are water-insoluble, and the poor solubility seriously restricts their absorption.
Poor solubility creates major obstacles for formulations and successful chemotherapy with ethaselen.
Poor solubility of a chemical entity is a major obstacle affecting its drugability [1].
The poor solubility of CNTs in most solvents limits their applications.
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