One control eye was also excluded from the analysis because of poor scan quality.
Scan-specific factors - complex activity distributions, poor scan conditions, variable noise levels - are all assessed and handled the same way.
PLC, the core element of modern automation systems, due to serial execution, exhibits limitations like slow speed and poor scan time.
Although it may be evident for some that clinical deterioration was the main cause based on medical record notes, it is difficult to differentiate between some causes such as poor scan quality of an OSH scan, redundant scanning given lack of accessibility of outside imaging, as opposed to lost/un-transferred disks in a retrospective analysis.
The scans of twenty-seven participants were excluded from the sample due to poor scan quality, low signal-to-noise ratio, or movement artefacts which did not allow for normal processing with the standard Freesurfer pipeline.
Six MRI scans were not used in the data analyses due to poor scan quality.
One healthy subject was excluded for the current study because of poor scan quality.
However, prospective multicenter studies have advocated for strict quality control criteria be implemented since boundary line errors due to poor scan quality and ring scan de-centration are common issues of clinical disagreement [ 26, 27].
From these 1923 participants we excluded from analysis 123 individuals with missing MRI variables (such as poor scan quality and artefacts), eight with prevalent dementia, and individuals with missing dementia status over the 10 years of follow-up (n=71 participants were seen only at baseline).
The analyses were applied to the whole sample (N = 390) excluding the poor quality scans and to a subsample comprising the scans with no, or minor defects (N = 344).
