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Although significant, CRP values at discharge would represent only a poor risk factor in the prediction of adverse outcome, with an area under the ROC curve of 0.58.
There is, for example, no distinction made between patients with one poor risk factor or three poor risk factors.
However, etoposide-containing protocols led to significantly improved survival in patients with at least one poor risk factor.
Evaluating whether physicians respond appropriately to poor risk factor control gives a different picture of quality of care.
The TRIAD CVD Risk Survey (38) found that missing medications was associated with poor risk factor control.
A binary variable was created to indicate whether pharmacy databases indicated an intensification of pharmacotherapy within 6 months after an instance of poor risk factor control during 2005.
Similar(38)
However, the multivariate analysis was strongly influenced by patients with poor risk factors.
The poor prognosis group is characterised by the presence of any of the poor risk factors mediastinal primary site, NPVM, AFP poor, HCG poor or LDH poor, that is, one or more poor risk factors are present.
This may be due to differences between poor prognosis patients with MGCT as to the type and number of poor risk factors (Decatris et al, 2000).
Similarly, the independent poor risk factors for DFS included older age >50 years, high WBC counts >50 000/μl, unfavorable-risk cytogenetics and TP53, RUNX1, WT1 and DNMT3A mutations.
The IGCC classification makes no clear distinction between the intermediate tumour markers and between the poor risk factors and is represented by a max score.
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