To assess whether the use of intraoperative opioids is associated with poor recurrence-free survival (RFS) and overall survival (OS) after lung cancer surgery.
The density of peritumoral CD68+ cells was associated with poor recurrence-free survival and overall survival [ 31].
Multivariate analysis indicated that poorly differentiated histology, macroscopic vascular invasion, tumour size, HAI and Ishak stage 6 were independently associated with poor recurrence-free survival.
The FGFR4 Gly/Gly genotype was associated with poor recurrence-free survival (P=0.036, Figure 2A), but not metastasis-free survival (P=0.351, Figure 2B).
They found that low serum IGFBP5 levels correlated strongly with a positive nodal status and disease recurrence and also predicted poor recurrence-free survival [137].
In conclusion, low MDR or increased MD during short-term endocrine therapy was independently associated with poor recurrence-free survival in patients with ER-positive breast cancer.
Several recent reports demonstrated that high-level expression of ERCC1 was correlated with platinum resistance and poor recurrence-free survival and OS in gastric cancer [ 35, 36].
Low expression of GPR49Δ5 mRNA is correlated with poor recurrence-free survival (P = 0.043) in STS patients and with the occurrence of late distant metastases (P = 0.025).
The log-rank test revealed that methylated cases of noncancerous liver were associated with poor recurrence-free survival (P = 0.031) and poor overall survival (P = 0.044).
Ishak stage 6 is not only associated with poor overall survival, but also poor recurrence-free survival and early recurrence rate.
In patients with Ishak stage 6, poorly differentiated histology and tumour size were associated with poor overall survival, and tumour size was associated with poor recurrence-free survival.
