Sentence examples for poor potency from inspiring English sources

However, when the nucleants are of a poor potency then a calculation of the fraction solid necessary to develop the constitutional undercooling required for nucleation needs to be performed.

Similarly, a series of bis(n -tacrine dimer series, bivalen -tacrineors andimeripheral seriesChE inhibivalentossess poor potency toward BmAChE.

Whatever the mechanism, this finding represents a previously unrecognized side-effect of crystalloid resuscitation in sepsis that is likely to contribute both to relatively poor potency and short duration of crystalloids as plasma volume expanders in sepsis.

The biological data revealed that most compounds exhibited moderate-to-excellent activity against HT-29, MKN-45, A549 cancer cell lines and relative poor potency toward MDA-MB-231 cell as well as hardly any cytotoxicity in normal PBL cell.

The inability of acutely administered Boc5 to elicit insulin responses under hyperinsulinemia may result from its poor potency as the compound is approximately 2700 times less potent than exenatide (Fig. 4B).

Consequently, these drugs exhibit poor potency and limited treatment success.

However, conjugation of the celecoxib analog with nile blue or sulforhodamine (e.g., 124 and 125) resulted in selective COX-2 inhibition with moderate to poor potencies.

An investigation of the length of the ester carbon chain revealed that the ethyl linker is optimal; both the phenyl ester 5 a and the phenpropyl ester 5 d showed poorer potency (Table 1).

Despite the specific inhibition by these peptides, their poor inhibition potency needs to be improved for further clinical application.

Thus, virological failure may result from suboptimal adherence, poor drug potency, drug resistance, or a combination of these factors [3].

Noticeably, injections of higher doses of ARM390 (30 and 60 mg/kg) also failed to produce DOR-eGFP internalization (data not shown), confirming the poor internalization potency of this compound in vivo.