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Soil type had a greater affect than management treatment, with poor persistence of the prairie community on topsoil plots largely irrespective of management.
Cells lacking the two known guanylyl cyclases exhibit both poor persistence and orientation.
Conversely, cells lacking PLA2 activity exhibit excellent orientation, but poor persistence, which is due to the reduced frequency of pseudopod splitting (Fig. 5B).
The sGCΔCat can not produce cGMP, but still localizes to the leading edge; these gc-null/sGCΔCAT cells still have poor persistence, but exhibit greatly improved orientation.
The poor persistence with these therapies is not surprising given the preventive nature of their use.
Patients aged ≥75 years had 19% greater odds of poor persistence.
Similar(32)
Elderly age, human insulin use, increased average insulin copayment, mental health comorbidity, and polypharmacy were all consistent predictors of poorer persistence with mealtime insulin.
36 Our results regarding adherence problems are similar to those described, and we also agree with the opinion of other researchers who believe that, in clinical practice, there may be certain factors concerning the use of generic drugs that could contribute to a lack of adherence and poorer persistence.
16, 17 In general, poor treatment persistence has been associated with higher health care costs and utilization.
Like the treatment of many other chronic diseases, adherence to biologic DMARDs can be poor with persistence rates ranging from 42-71% [ 1].
Likewise, in a four-year follow-up study of 140 ADHD children and 120 community controls, Biederman et al. found that family adversities were highly associated with a poor outcome (persistence of ADHD) [ 67].
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