Sentence examples for poor pathway from inspiring English sources

This may reflect interactions between these pathways, an interplay between the WNT and cadherin pathways is known to exist [49], or may be a consequence of poor pathway annotation.

The lower complement of PIKs in unicellular eukaryotes relative to metazoans suggests poor pathway redundancy and enhanced probability of essential function to the parasite.

There are two pro-poor pathways to achieving UHC within a generation.

However, the pharmacodynamic analysis performed in the 13 patients treated at those dose levels revelled poor mTOR pathway inhibition at doses <5 mg of sirolimus.

This, in combination with sulfonates' poor NFκB pathway inhibition, led to the fumarate pair emerging as the best candidates, and GTCpFE was selected as a prototype for further detailed study.

Most studies show that most terminally ill patients and their relatives wish death to take place at home [ 3, 25- 27] and an institutional death may be a direct consequence of a poor palliative pathway at home.

Whilst invaluable and in many ways the best we have, a major problem with these efforts is that the information content of these diagrams is frequently limited and visualizations of these systems are of variable and often poor quality; Pathway components are often labelled using inconsistent nomenclature systems and depicted using a variety of shapes (glyphs) to illustrate component 'type'type

Perhaps there are, for the rich, other ways of being prosperous, and for the poor, other pathways out of poverty than those we know.

These factors were also highlighted in a survey of junior hospital doctors who cited unattractive working conditions, long working hours and poor career pathways for junior hospital doctors [ 42] as factors prompting the emigration of Irish trained doctors.

Expression of foreign pathways often results in suboptimal performance due to unintended factors such as introduction of toxic metabolites, cofactor imbalances or poor expression of pathway components.

Objective: To identify patients with poor tissue factor pathway inhibitor (TFPI) response to heparin and observe any association with increased risk of excessive coagulation activation, morbidity, or mortality.