Sentence examples for poor localization from inspiring English sources

Despite the recent expansion of peptide drugs, delivery remains a challenge due to poor localization and rapid clearance.

These liposomes, otherwise, exhibit long circulatory behaviour in control animals, with poor localization to the liver and spleen.

As poor localization and stability have been the greatest challenges to their clinical translation, a variety of nanocarrier systems have been developed to directly address these limitations.

However, orally administered drugs suffer from poor localization and therapeutic efficacy due to various physiological conditions such as low pH, and high shear intestinal fluid flow.

Among many factors, late diagnosis and poor localization of metastatic lesions in patients with melanoma results in high mortality from this cancer [2].

Next, in order to effectively circumvent poor localization (low precision positioning), we decompose the space into sectors, with each sector being small enough to have reasonable localization accuracy within itself.

These results confirmed that FUS-MB is possible in transgenic animals using our simple benchtop sonication system, albeit with poorer localization accuracy.

In regards to the GC-poor localization of the genes that are not expressed in any of the three adult mouse tissues considered here, the notion that they may be implicated in developmental processes is supported by several studies.

Poorer localization of the Botox within the musculature of the vocal fold (unwanted spread from injection sites) because of hampered diffusion resulting from changes in the interstitial ground substance (Thibeault et al 2002) and altered architecture of connective tissues within the TA muscle (Kahane 1987; Shaari et al 1991).

However, they are prone to error from poor head localization [1, 6].

This poor frequency localization makes it difficult for CP-OFDM systems to respect stringent specifications of spectrum masks.