Sentence examples for poor invasion from inspiring English sources

Histomorphological studies have reported that preeclamptic pregnancies are characterized by defective remodelling of maternal spiral arteries due to poor invasion by trophoblast cells in the decidua [3].

Poor invasion of trophoblasts are thought to lead to such conditions as pre-eclampsia yet many of the steps involved in trophoblast invasion are poorly understood.

In the invasion assays, the parental strain GD201008-001 dispoored poor invasion of HEp-2 cells (<0.0005%) and there were no significant differences in corresponding activity exhibited by the Δ xf and CΔ xf strains (data not shown).

The selective loss of genes primarily responsible for the first steps of infection may contribute to the poor invasion ability and the attenuated nature of the 4a L99 strain.

Of interest was the very poor invasion inhibitory activity of dirithromycin (521 μM), which was 52-fold less potent than azithromycin, even though the IC50 values determined using 1 cycle growth assays were very similar (dirithromycin, IC50 90hr 8 μM; azithromycin, IC50 90hr 7 μM; Table  1).

As discussed, poor trophoblast invasion of maternal spiral arteries is a key feature of preeclampsia.

Positive Nectin-2 and DDX3 expressions are associated with poor differentiation, invasion, metastasis, and poor prognosis of PDAC.

The role of HMGA2, which is a mesenchym-specific factor was thus strongly correlated with poor differentiation, invasion and metastasis of oral cancer [ 11, 25, 26].

This is the first study to implicate the DDAH/ADMA pathway as a mechanism that might underlie the poor trophoblast invasion seen in this common pregnancy disorder.

The poor dsDNA invasion (DSI) capacity of PNA-ONs at physiological salt concentrations was somewhat improved by conjugation with the intercalator 9-aminoacridine, and using short LNA-containing ONs as openers enhanced invasion into supercoiled DNA.

The mechanisms responsible for the poor trophoblast invasion and inadequate remodelling have yet to be determined although a reduced capacity to invade and/or increased sensitivity to apoptotic stimuli may play a significant role.