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As well as the risk of these possible adverse effects not all patients respond to these treatments and non-adherence to treatment is common due to issues such as complex treatment regimens, poor inhalation technique and delayed results [10] thus there is an unmet medical need for complementary therapies for asthma.
Poor inhalation technique results inter alia from problems in handling the inhalation devices or knowledge deficits.
Also, several studies have highlighted poor inhalation technique with DPIs in clinical practice [ 25, 26].
Spacers are used to minimize problems of poor inhalation associated with pressurized MDIs, but they present problems of their own.
Another concern with adherence measurement of ICS is the fact that registered doses may not have been administered correctly due to poor inhalation technique.
Patient outcomes in obstructive lung diseases in routine care are not as good as in clinical trials due to poor inhalation technique [ 19].
Similar(52)
96 Poor inhaler technique is a variety of unintentional nonadherence 96 and it is common in asthma, as the most important drugs used for its management are administered by inhalation.
Age, underlying disease, malnutrition, infections, and PaO2/FiO2 ratio are commonly utilized tools that may be used to predict poor outcome after inhalation injury.
Age, underlying disease, malnutrition, and infections have been studied as prospective clinical predictors of poor outcome after inhalation injury in addition to the PaO2/FiO2 ratio [ 6].
The arterial oxygen tension (PaO2)/fraction of inspired oxygen (FiO2) ratio is a parameter that is widely used to define acute respiratory distress syndrome (ARDS) and – along with age, underlying disease, malnutrition, and infection – it has been proposed to be a prospective clinical predictor of poor outcome after inhalation injury [ 6].
In addition to damage caused by the fire, smoke resulted in a significant increase in emergency room visits due to asthma, respiratory problems, eye irritation, and smoke inhalation; the poor air quality caused San Diego County schools to close for a week.
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