Sentence examples for poor imputation from inspiring English sources

We excluded SNPs with minor allele frequency of <0.01 and those with poor imputation quality based on the estimated correlation between imputed and true genotypes (r < 0.3).

35 None of the questionnaires has an official algorithm for imputing individual missing answers; fortunately most measures with such algorithms use poor imputation methods.

Variants with poor imputation quality scores (r2 less than 0.3) and minor allele frequency less than 1% were removed after imputation.

An additional 3 SNPs were removed due to poor imputation quality or ambiguous coding.

Analysis of genomic regions with poor imputation quality revealed 5039 SNP that are most likely misplaced.

Poor imputation quality along entire chromosomal segments results from intra-chromosomal misplacement of adjacent SNP.

Specifically, if missingness in the predictors is dependent on the outcome, then approach (1) will lead to poor imputations.

Its average RMSE value is often 0.5 higher than the second poorest imputation method.

The aim was for good characterisation of eQTL down to low frequency variants, though this is complicated by power and poorer imputation accuracy at such frequencies.

However, we do recognise this as an issue and so have added the following caveat: "The aim was for good characterisation of eQTL down to low frequency variants, though this is complicated by power and poorer imputation accuracy at such frequencies".

Nonetheless, genes that were lowly expressed in all samples showed poor correlations between imputed and observed expression across the 52 samples we used to test the imputation model.