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The AUC of T1 endocan concentrations for prediction of poor evolution is shown in Fig. 3.
A possible association of BL underdosing with poor evolution of infection and organ failures would need more precise evaluation.
In patients with ARDS, plasma endocan concentrations 24 h after diagnosis may be useful to predict poor evolution.
In the multivariate analysis, APACHE II score (but not endocan at T1) was retained as the best predictor of poor evolution (OR 1.149 [1.067–1.237], p < 0.01).
We plotted sensitivity and specificity on a ROC graph and the area under the curve (AUC) was calculated for the different variables to predict mortality or poor evolution.
Plasma endocan concentrations were statistically significantly higher in patients with poor evolution than in those with good evolution at T1, but not at T0 (Fig. 2).
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The poorer evolution of vascular and renal TOD in females, particularly among those with diabetes, may be due to the fact that women show greater stiffness values in the prepubertal period, and this stiffness moreover increases after menopause.
However, the practical performance of bulk SnO2 is far from the ideal case which has been limited by several factors such as short lifetime of the excited-state carrier (10−12 s), poor oxygen evolution reaction kinetics, and short hole diffusion length (2 4 nm) [9, 10, 11, 12, 13, 14, 15].
We can conclude that genomic damage has an independent prognostic value of poor clinical evolution in NSCLC.
In conclusion, the location of p53 mutations might be considered as a prognostic indicator for the evaluation of poor clinical evolution in NSCLC patients.
Our purpose was to study the prognostic value of p53 alterations and to determine whether some specific mutation type in the p53 gene could be associated with poor clinical evolution in non-small-cell lung cancer (NSCLC) patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com