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Malignant tumors composed of moderately differentiated cells can also contain regions of poor differentiation.
Tumours with poor differentiation express higher VEGF-A levels (⩾median) than highly differentiated tumours.
Tumors of larger size and poor differentiation are more invasive and progressive than smaller and well-differentiated ones.
Also note the poor differentiation of the prostate zonal anatomy.
LCC are usually tumors of poor differentiation and high malignant potential.
Ito et al. have suggested cyclin A2 overexpression is directly related with poor differentiation [31].
However, there was no correspondence with tumor progression toward poor differentiation (Table 5).
However, we have demonstrated that high ID2 expression in nuclei seems to be correlated with poor differentiation of the tumor.
Thus, overexpression in pancreatic tumors suggests Stx receptors as potential markers for poor differentiation in this type of cancer.
There was poor differentiation from background and other inflammatory debris.
Positive DDX3 expression is associated with poor differentiation of PDAC.
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