Sentence examples for poor detoxification from inspiring English sources

Some of these biomarkers are indicative of vitamin E insufficiency, increased oxidative stress, and poor detoxification and are associated with the severity of the disorder [ 7- 10].

The reduction in this essential detoxifying enzyme can explain the poor detoxification in patients with ASD, leading to the Hg and Pb toxicity discussed above.

ORs per "high-risk" (hypothesized poor detoxification) allele (PON1 108T, FMO1 9536A, and BCHE539T) were greater among children whose homes had been treated during childhood than among children whose homes never had been treated.

Given the emerging evidence connecting poor detoxification of environmental toxins to the biomedical and clinical presentation of ASDs, an intervention that temporarily decreases environmental exposure may positively impact phenotypic presentation [ 55].

All measured parameters demonstrated almost 100% sensitivity and very high specificity, which also confirmed the hypothesis that autistic patients are poor detoxifiers, unable to readily excrete toxic substances (e.g., Hg and Pb), and suggests that reduced GST activity and depleted vitamin E are two critical factors related to poor detoxification.

In many cases, these latter mutations simply act to increase expression of enzymes that are still relatively poor catalysts of the detoxification reaction required.

These range from individuals with regular enzyme and detoxification functions to poor metabolizers with low or no enzyme activity [ 4, 5].

The expression of MRJPs, immune genes, and genes encoding detoxification enzymes declined due to poor diet exclusively at later ages.

Thus, "His113" poor activity genotype was responsible for deficient detoxification, accumulation of genotoxic metabolites and probably breast carcinoma initiation.

Service/treatment systems' limited aftercare options, inadequate services to address medical and psychiatric comorbidities [ 2, 13], overwhelming paperwork demands, [ 6] and poor integration between all phases of care from detoxification to community reintegration have also been noted.

The 279 study participants were treated for heroin and/or cocaine dependence on detoxification wards in two hospitals in a poor, predominantly Hispanic, neighborhood in New York City.