Suggestions(2)
Exact(4)
A few field-deployable assays (strip or lateral-flow immunoassays) are available but suffer from major limitations including poor detection limit and inability to provide quantitative results.
For example, Nga et al. [53] have recently described a multiplex real-time PCR assay that targets S. Typhi and S. Paratyphi A. The sensitivity of the assay on blood samples was low with only 42% sensitivity for S. Typhi and 39% sensitivity for S. Paratyphi A. This poor sensitivity is most likely due to the poor detection limit of the assay.
A major problem is the poor detection limit of currently available hormone assays for estradiol and testosterone and their cross-reactivity with other hormones in the immunoassays, which is of concern especially in cord blood samples.
At position 1711, chromosomes 5 and 11 have a C as does the tissue; however, chromosome 3 has a T. A weak heteroplasmic signal is evident by a minute T peak, but because of the poor detection limit of fluorescent sequencing, this peak is virtually equivalent to background.
Similar(56)
However, conventional iodometric titrations suffer from several limitations like losses of iodine, titration error, lack of suitable indicators, and poor detection limits.
Referring to Table 3, the relatively poor detection limits for Mn, Fe and Si are due to elevated blank levels caused by contamination of cones by sample matrix (Mn and Fe) as well as by contributions from the ICP torch (Si).
Hence, this type of detection is not satisfactory because of both poor selectivity and poor detection limits.
This small injection volume results in poor concentration detection limits and relatively small numbers of protein and peptide identifications.
However, sensitivity is poor with a detection limit of only 0.3 nM.
X-ray diffraction of blackened particles produced no discernable pattern, indicating concentrations below the detection limit, poor crystallinity, or both.
The cut-off developed here is not applicable to two of the rarer genotypes in genogroup II (GII-7 and GII-8), because the real time RT-PCR assay has poorer efficiency (a higher detection limit) for these genotypes (J. Gray, personal communication), so the Ct values do not represent the same faecal viral loads as for the other genotypes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com