Sentence examples for poor complementarity from inspiring English sources

Exact(2)

The bias arising from poor complementarity between primers and 16S rRNA genes in particular taxa leads to underestimation of these taxa in a microbial community.

No interaction was observed with Lys and, moreover, the pyrrolidine group clashed with Trp on the N-terminal lobe wall of the active site, further supporting poor complementarity of this compound with p110γ.

Similar(57)

The interface between peptide and TCR exhibits extremely poor shape complementarity, and the TCR beta chain complementarity-determining region 3 (CDR3) has minimal interaction with the dEV8 peptide.

The peptide makes few specific contacts and exhibits extremely poor shape complementarity to the MHC groove, which facilitates the presentation of a degenerate array of sequences.

The open arrow indicates poor shape complementarity at the putative second LapG binding site.

Yet, modeling GAGs has been problematic due in part to their polyanionic nature and poor surface complementarity.

The net result is a transition from a four-helix bundle with poor shape complementarity with LapG to a two-helix bundle and an overall shape that is able to accommodate LapG.

Similar TCR contact positions, but whose exact amino acid content can vary, coupled with relatively poor interface shape complementarity, may explain the flexibility and short half-lives of many TCR interactions with pMHC.

The former usually are located in intergenic regions and share only poor and incomplete complementarity with target sequences, which complicates computational target predictions.

In contrast to computational predictions of eukaryotic microRNA targets, predictions of bacterial sRNA targets are complicated by poor and incomplete complementarity.

Yet, by and large, crystallographic structures of TCR pMHC interfaces do not have hallmarks of high-affinity complexes: the interfaces tend to be relatively flat, with poor packing, suboptimal surface complementarity and buried water molecules [ 5].

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