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These measures included removal of all data from 21 animals due to a high rate of missing genotypes and exclusion of 130 SNP due to poor assay performance.
Discrepancies between studies could be due to low sample sizes, poor assay performance, and differences in techniques adopted by laboratories.
First, the high sensitivity of BSI, with all Galectin-7 samples being within the LOQ, provides reasonable confidence that poor assay performance is not the discordance of the tissue serum results.
Similar(57)
A similar LIA reaction environment with CL (diphosphatidylglycerol) instead of PG demonstrated a significantly poorer assay performance which underlines the importance of the phospholipid nature for specific aPL binding.
The validation cohort consisted of samples with varying DNA quality, to assess assay performance.
NB supervised and ensured CO3-610 assay performance.
Overall assay performance based on methylated controls and clinical FFPE tumour samples indicated consistent assay performance.
Inter-assay performance is comparable to intra-assay performance.
VQ contributed to the assays performance.
Assays demonstrating poor or marginal performance were flagged.
Only 1 of these 4 samples showed a poor performance on the assay (see result section).
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