Sentence examples for poor accumulation from inspiring English sources

Graphene oxide (GO) is a versatile platform for drug delivery, but poor accumulation at the tumor site limits the translation of this technology.

However, the expression of the biosynthetic enzymes responsible for the synthesis of unusual fatty acids typically results in poor accumulation of the desired product.

At the other extreme, the system harboring the ADO form Synechococcus sp. RS9917 produced very low amounts of the short-chain alkanes, primarily due to poor accumulation of the enzyme in E. coli.

Cancer stem cells are known to be highly chemo-resistant, and this phenotype is believed to be attributed to their self-renewal capability, resistance to DNA damage and other apoptosis-inducing stimuli, as well as their relatively poor accumulation of cytotoxic drugs5.

WT myc-tagged KREPA3 was incorporated into ∼20S editosomes and had no effect on cell growth or RNA editing (Fig. 1A to D), but simultaneous expression of untagged KREPA3 resulted in the relatively poor accumulation of myc-tagged KREPA3, presumably because myc-tagged KREPA3 is less efficiently incorporated into or retained by editosomes than the untagged protein.

Likewise, consistent with the poor accumulation of carotenoids in BF, these organelles were not observed in the ripe BF.

This redirection, however, may come at a price of poor biomass accumulation, reduced cofactor regeneration and low recombinant enzyme expression.

However, the monovalency and the rapid renal elimination of scFvs result in poor tumor accumulation and retention.

One possible explanation for the suboptimal crizotinib ALK binding in RR cells is related to the relatively poor drug accumulation in this cell subset.

The existence of this process can enlarge the gas exploration realm to the "poor" gas accumulation area, i.e., gas reservoirs can still be found in the uplift area where gas reservoirs were formerly not believed to develop.

Secondly, the poor lignin accumulation in the basal culm and the weak stem strength under high N application were the results of lower related enzymes activities, such as phenylalanine ammonia-lyase (PAL), tyrosine-ammonia-lyase (TAL) and cinnamyl alcohol dehydrogenase (CAD) (Wang et al., 2012; Lu et al., 2014).