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To get drug developers to focus on these relatively small pools of patients, the federal government offers inducements like a 50 percent research-and-development tax credit as well as a longer period of market exclusivity (seven years after Food and Drug Administration approval, rather than the typical five).
Increasingly, trials of new drugs are conducted in many countries, to ensure compliance with differing regulatory requirements, because emerging markets offer lower costs for clinical development, and to get access to different pools of patients.
Interestingly, α-enolase was recognised by IgG from all pools of patients in both extracts.
A limited number of proteins were recognised by IgG from all pools of patients.
The proteomes of virion-enriched fractions purified from plasma pools of patients with dengue fever or severe dengue were compared.
Interestingly, α-enolase was recognised by immunoglobulin G (IgG) from all pools of patients in both extracts.
Similar(46)
Insurers would be left with a sickly pool of patients.
"There are existing abortionists who are competing for a pool of patients that is shrinking," Dr. Levatino said.
Insurers, with a sickly pool of patients, would raise prices in 2015.
That could leave insurers with a sick, expensive pool of patients.
That pool of patients, whom Dr. Hirsch called "Rezulin survivors," might make Actos and Avandia appear safer than they really are, he said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com