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A major design issue when using DNA pooling technologies is the measurement error as compared with the gold standard method of individual genotyping.
Advantages of DNA pooling technologies include (a sometimes substantial) reduction in genotyping cost when performing multi-stage association studies to identify disease susceptibility genes.
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Herein, we used a DNA pooling technology to perform the first genome-wide association study in Behçet's disease.
Using DNA pooling technology and the Affymetrix 500K arrays, we identified possible candidate gene associations with Behçet's disease in a cohort of 152 Behçet's disease patients and 172 healthy ethnically matched controls.
Meme media and meme pool technologies will work as such extended Open Hypermedia Systems technologies to annotate, re-edit, and redistribute Web-published assets.
To the right, the stand of Renault's strategic-alliance partner Nissan; the two companies increasingly pool technology so it's the sales performance of their so-called B platform, which the Clio shares with some 20 other models, that's important for economies of scale – not just the sales of the Clio alone.
Pooling patented technologies in this way encourages good interoperability of products from different manufacturers and helps greatly with consumer take-up.
And G.E. is pooling its technology for organic light emitting diodes — usually called Oleds — with that of Konica Minolta, in hopes of jointly developing various lighting products.
The most sought-after resources were those that were a given research group could not ordinarily access within its own pool of technologies, materials, and expertise.
But the strategy, says Michael Cleare (pictured at left), executive director of Columbia's Science and Technology Ventures, "is to pool our technologies and create a start-up company in Singapore or in the United States, depending on where is the best place to do it".
For data analysis, a canonical sequence reference file and a plug-in for the Ion-Torrent server are provided by the supplier of the PCR-primer pool (Life Technologies, Carlsbad, USA).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com