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The NCP is a function of the difference between the case and control allele 2 frequencies, the quality of the pooling estimate of these probabilities, the number of cases and controls, the number of replications of DNA measurements of each pool, and the size of each pool.
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The necessary precondition for pooling estimates is that the studies and results are reasonably homogeneous.
The accuracy of DGV was evaluated by pooling estimates from a 5-fold cross-validation strategy.
The accuracy of DGV was evaluated by pooling estimates using a 5-fold cross-validation strategy.
However, pooled estimates mask essential information when variability in estimates is mainly due to factors such as differences in study design or populations, and a better understanding may be gained from looking at these studies without pooling estimates.
Petti S. Pooled estimate of world leukoplakia prevalence: a systematic review.
These states have a coefficient of -0.246 which is considerably lower than the pooled estimate.
We investigated for potential influence of bias on the pooled estimate by aspects of the study quality criteria.
Random effects analysis assumes a range of treatment effects and incorporates inter-study variation into the pooled estimate.
Considerable heterogeneity did not justify a pooled estimate.
We found a moderate heterogeneity and a statistically significant pooled estimate that favored HSCT.
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