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The individual phenotypes were summed per cage to obtain pooled records.
Pooled records were obtained by summing individual phenotypes according to Equation (3).
The direct indirect animal model on pooled records failed to converge, confirming that direct and indirect (co variances cannot be estimated from pooled data.
Using the PRISMA flow diagram for reporting systematic reviews and meta-analyses (see online supplementary appendix A), 38 all pooled records will be de-duplicated with additional filters added.
The traditional animal model on pooled records yielded estimates of σ A 2 and σ E * 2. These estimates did not differ significantly from the true σ A T 2 and σ E * 2 (Table 4), where (13) σ A T 2 = σ A D 2 + 2 n − 1 σ A DI + n − 1 2 σ A I 2 (derived by [ 14]) and (14) σ E * 2 = n σ E D 2 + 2 n − 1 σ E DI + n − 1 2 σ E I 2 (analogous to [ 17]).
Alternatively, data can be obtained on group level, resulting in pooled records.
Similar(51)
Second, the simulated pooled records were analysed with the following traditional animal model in ASReml v3.0 [ 20]: (9) y * = μ * + Z * a + e *, where y*, μ* and e* are as explained above; Z* is an incidence matrix linking the pooled records to A's (each pooled record was linked to the A's of the four group members); and a is a vector that contains A's.
As the cytokine response detected by Elispot or CBA did not differ significantly between RASFs and OASFs, median values of pooled recorded data from these experiments are indicated with horizontal line in Figure 2a, b.
It follows from Equations (1) and (3) that, with social interactions, a pooled record consists of the AD and ED of each group member, as well as their AI and EI that are expressed n – 1 times: (4) P * = ∑ k = 1 n A D k + E D k + n − 1 A I k + E I k.
Rather than using onpatient as a place to pool records created by other people, drchrono puts a strong emphasis on primary data recorded by the patients themselves, by way of smartphones and apps ("mobile phones are the perfect for recording health data and sharing this data back to a doctor," Kivatinos explains; the app is iPhone only right now); diagnostic cuffs, and more to come apparently.
Patient characteristics and incidence rates were assessed for all three clinical outcomes, based on GP, hospital, paired GP/hospital (similar diagnoses recorded simultaneously in both data sets) or pooled GP/hospital records (diagnosis recorded in either or both data sets).
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