As a result, efforts have been made to pool the results of many smaller trials to look for safety problems.
The University of Pittsburgh researchers didn't conduct a new study, but used some sophisticated statistical techniques to pool the results of nine that had already been done.
Meta-analysis was used to pool the results of studies investigating the efficacy of orlistat and sibutramine compared with placebo, measured by the proportion of subjects with ≥5% weight loss after 1 or 2 y of treatment.
An attempt was made to pool the results of studies reporting on the same outcome, measured at the same time points, and using the same method of measurement.
Due to the different techniques used to measure the results, particularly the CI, it was not deemed accurate enough to pool the results.
We could not pool the results of the previous 2 trials which evaluated this outcome to quantitative synthesis due to differences in specific treatments (non-extraction vs. extraction).
Loop through the CDR data, compute inter-observation times for each origin-destination city pair, and pool the results into inter-observation distributions.
Because of the differences in definitions of essential (primary) outcome measures, we decided not to pool the results for a formal meta-analysis.
An attempt to pool the results of these four studies in the form of a meta-analysis was deemed to be unfeasible due to the extent of heterogeneity between the studies [25].
Therefore, we conducted this systematic review and meta-analysis not only to pool the results from relevant studies, but also to compare the diagnostic accuracy of presepsin with other biomarkers in diagnosing sepsis.
We use the projected total impacts in Phase 2 and 3 separately, and then, to increase power, we pool the results for the two phases on the assumption that the true relative impacts for the two phases are the same.
