To determine the effects of DHC-1 depletion on meiotic prophase, we dissected animals after exposure to auxin for several hours, so that a pool of nuclei had entered and progressed through early prophase in the absence of DHC-1.
Pools of 20 nuclei per replicate were averaged.
In addition, nuclear pores do not restrict diffusion of low molecular weight solutes like GSH [14], which could possibly difficult the establishment of a specific pool of GSH within the nucleus.
This finding is compatible with a distinct pool of GSH in the nucleus that is comparatively resistant to BSO depletion.
Unlike diploids, haploids express Far1, a protein that is important for mating and sequesters a pool of Cdc24 in the nucleus.
The pool of dNTPs in the nucleus is tightly regulated and studies have speculated that RNR inhibition can increase the likelihood of nucleoside analog DNA incorporation by reducing the pools of endogenous nucleotide concentrations [ 27, 34].
However, it is important to note that this motion would presumably not disturb the Bcd gradient within the nuclei, formed by the pool of Bcd localized within nuclei or energids.
Quiescent macrophages constitutively expressed HMGB1 and maintained an intracellular "pool" of HMGB1 predominantly in the nucleus (Fig. 5A, left panels).
In the spinal trigeminal nucleus, a pool of WDR neurons is located rostrally, in the Sp5O, about 3 mm apart from the superficial laminae of the MDH where the NS neurons are situated [36], [51] [56].
Since ERK1/2 are activated in the cytoplasm and are continuously inactivated in the nucleus, the pool of nuclear phospho-ERK needs to be continuously replenished from the cytoplasm in order to maintain a sustained level of nuclear phosphorylation [24].
