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Here we show that such efforts could successfully pool databases of genotype and exercise information across multiple countries to enhance detection of the genomic regions implied in exercise behavior.
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Pooled databases for each wave were then merged into one longitudinal pooled database.
The economists who established the SSGAC are Dan Benjamin, David Cesarini, and Phil Kollinger, and the work of the SSGAC is characterized by its ambition and may have been motivated by The Wellcome Trust Case Control Consortium attempts to improve the understanding of the aetiological basis of several major causes of global disease by pooling databases collected by individual research teams.
We do not make our analysis using directly the pooled database since all the control explanatory variables are not available in each waves, which is a limitation of this database.
The model for OS was developed based on the 888 patients pooled database, of which 556 (63%) died during the observation period.
The aims of this study were to analyze factors for predicting cardiac death and to create a prediction model incorporating MIBG imaging based on the Japanese multicenter pooled database.
The large size of the pooled database allowed us to investigate in greater detail hypotheses not properly tested in the original studies, in particular, whether the frequency of chromosome-type and chromatid-type aberrations has a different predictive value for cancer risk.
In majority of the reports comparing outcomes between participants and non-participants of clinical trials, however, the non-participant 'controls' were chosen from differently pooled database, which could include baseline imbalances between groups and hindsight bias (Davis et al, 1985; Braunholtz et al, 2001; Peppercorn et al, 2004).
The study patients were selected from the pooled database according to the following criteria: unilateral stage pT1 3, N0 1, M0, HER-2-positive invasive breast carcinoma diagnosed between 1984 and 2006, no neoadjuvant chemotherapy and surgical treatment with either breast-conserving therapy or mastectomy with sentinel node biopsy or axillary lymph node dissection.
DNA testing companies, which compete for customers, do not pool their databases, so people often submit samples to more than one.
"Headquartering Cloudera's EMEA operations in London, at the heart of its technology cluster, will enable us to develop closer ties with key customer and partner organizations, and gives us access to a diverse and highly skilled pool of database architects and data scientists," said Ross Hinchcliffe, vice president of EMEA at Cloudera in a statement.
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