Exact(9)
Therefore, this model provides reasonable interpretation for both the plus-end tracking and the microtubule polymerization promoting activities of EB1.
The protein was later discovered to possess tubulin binding ability, and was renamed as tubulin polymerization promoting protein (TPPP) [ 2].
p25α/tubulin polymerization promoting protein (TPPP) is an oligodendroglial protein that plays crucial roles including myelination, and the stabilization of microtubules.
Tubulin Polymerization promoting Protein 1 (TPPP1) alters MT dynamics by driving MT polymerization as well as stabilization, via increasing MT acetylation.
For example, proteins involved in microtubule dynamics that are modified by O-GlcNAc include microtubule-associated proteins 1, 2, and 4 (Ding and Vandré, 1996), tubulin polymerization promoting protein (Vosseller et al., 2006), and Tau (Liu et al., 2004).
To characterize the inclusion-bearing cells, anti-S-100 was used as a marker of Schwann cells [ 21], anti-tubulin polymerization promoting protein (TPPP /p25α as a marker of oligodendroglia [ 22], and anti-phosphorylated neurofilament as a marker of axons [ 23].
Similar(51)
The interplay between these two signals, reconstructed across four time points, suggests that F-actin polymerization promotes branch extension.
Conversely, actin polymerization promoted by Buserelin-stimulated GnRHR and GnRHR-DesK191 was significantly decreased in non-adherent (p<0.05; Figure 2B).
However, good evidence has been presented that actin polymerization promotes membrane invagination as well as scission (Galletta and Cooper, 2009; Anitei and Hoflack, 2012).
In U2OS cells, this 'vectorial' actin polymerization promotes elongation of the actin filament bundle with a rate of ∼0.25 μm/min (Hotulainen and Lappalainen, 2006).
HIV-1 Tat (Transactivator of transcription) is a multifunctional protein in that it suppresses DNA polymerization, promotes tRNA placement onto HIV RNA, alters chromatin structure, phosphorylates RNA polymerase II and is responsible for viral gene transactivation [ 14].
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