Sentence examples for polymerase speed from inspiring English sources

This polymerase speed effect does not necessitate any dependence of a downstream splicing decision on an upstream decision the multiple sites of alternative splicing can be independently but similarly influenced by polymerase speed.

One potential explanation for this effect is promoter-dependent polymerase speed: slow RNA synthesis favors inclusion of cassette exons with weak splicing signals, while fast RNA synthesis favors their exclusion (Fededa et al., 2005; Dujardin et al., 2014).

In a plethora of examples Pol II was observed to pause downstream of poly(A) signals in vivo and in vitro and these examples have now been generalised by genome wide studies showing that polymerase speed decreases after many poly(A) signals [23,40,106 110].

Although many base modifications, such as 6mA, 4mC, 5hmC and 8-oxo-guanine, are readily detectable in SMRT sequencing [ 16, 17, 20, 21], the kinetic signature of 5mC is more subtle, requiring high sequencing fold coverage to make out the small effect on polymerase speed.

Size selection is achieved because standard Taq DNA polymerase extension speed is on the order of 700 800 nucleotides per minute at 72°C.

By putting fewer nucleotide bases into solution, the researchers reduced the polymerase's transcribing speed from about 45 bases per second to 1 base per second.

It is possible that the TDRP observed here is the result of changes in FV biology, such as polymerase fidelity, replication speed, and/or transmission modes.

In addition, in the presence of DNA polymerase inhibitor, fork speed is impaired and replication at these loci risks to remain partial, making the unreplicated regions more prone to breakage [ 30].

It is well known that long stretches of identical nucleotides in the template strand may cause a "stuttering" behaviour of the Taq DNA polymerase reducing the speed of the elongation process or causing the enzme to fall off the template strand.

A version of high speed DNA polymerase was used to shorten the amplification time.

Such an evolutionary path is not without consequence, though, as the speed of polymerase synthesis is tied to mutation rate [6].