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The differences in nucleotide binding affinity shown by mutants V250A and V250F with respect to the wild-type DNA polymerase agree to a role for Val250 as a metal B dNTP complex ligand.
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The critics agree that contamination can be a serious issue when using polymerase chain reaction technology.
These results agree with the controversial role of H2A.Z in the transcription of RNA polymerase II genes [ 57].
Author's response #2: I agree that it is difficult to exclude the possibility that ribozyme RNA polymerases existed, and their functional replacement with protein counterparts would indeed be in agreement with design-by-contract.
Voters agree.
Regulators agree.
Authors agree.
(Uniformly agree).
We do not agree.
Observers agree.
* Agree or strongly agree.
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