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Epidemiologic studies have shown conflicting results regarding the role of traffic pollution in the development of allergic disease.
The role of air pollution in the development of new-onset asthma remains controversial, and the contribution of this environmental risk factor to the pandemic remains unclear (Eder et al. 2006; Sarnat and Holguin 2007).
8 In the case of respiratory and allergic diseases, air pollution is known to result in acute exacerbations of existing conditions, but there is uncertainty in the role of air pollution in the development of adult-onset disease.
Several studies support the role of air pollution in the development of asthma in childhood (Anderson et al. 2013; McConnell et al. 2010), but not all (Mölter et al. 2015).
Biologic mechanisms by which these exposures may lead to RA inflammation, oxidative stress, and immune suppression have also been correlated with ambient air pollution (Donaldson et al. 2001; Omara et al. 2000), leading to a hypothesis for the role of air pollution in the development of RA.
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It is well known that air pollution exacerbates symptoms in individuals already suffering from asthma and allergic conditions; 9 10 31 32 however, the role that air pollution plays in the development of asthma and allergies is less clear.
Consequently, specific sets of distinct species reflecting levels of pollution were instrumental in the development of a practical tool.
The role of traffic-related air pollution (TRAP) exposure in the development of allergic sensitization in children is unclear, and few birth cohort studies have incorporated spatiotemporal exposure assessment.
Taken together, there is growing support for the relevance of traffic related pollution in the exacerbation and development of asthma.
The Bohai Rim, covering three provinces and two municipalities in China, lies in a region that is sensitive to profound conflict between socioeconomic development and environment pollution in the process of sustainable development.
In contrast, our results suggest a marginal contribution of air pollution to the development of diabetes in smokers and ex-smokers.
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