Sentence examples for pol i from inspiring English sources

DNA unwinding between the Pol I protrusion and clamp domains enables cleft contraction, resulting in an active Pol I conformation and RNA synthesis.

RNA polymerase I (Pol I) is a 14-subunit enzyme that solely synthesizes pre-ribosomal RNA.

Importantly, these data present a mechanistic basis for the requirement of A12.2 in Pol I termination.

Recently, the crystal structure of apo Pol I gave unprecedented insight into its molecular architecture.

It is well-known that MYC regulates rRNA synthesis and ribosome biogenesis through direct activation of Pol I and transcriptionally increasing the levels of Pol I subunits26.

pPol-I-luc (with a human RNA pol I promoter) has been described elsewhere69.

Rapidly growing cancer cells are characterized by increased Pol I-mediated transcription and, consequently, nucleolar hypertrophy.

Yet evidence linking FACT to Pol I-dependent transcription in cells was missing.

Transcription in eukaryotes is performed by three different RNA Polymerases, Pol I-III.

Eventually, he was arrested and is currently serving in Pol-i-Charkhi prison.

T. brucei has also co-opted the Pol-I machinery for VSG expression, leading to the formation of a novel extranucleolar, telomere-associated Pol-I compartment.